Nicholas Alfonso was born on May 23, 1965, in New Orleans, Louisiana, to Jerry and Ramona Alfonso. He is married to Lisa Christofi Alfonso, and they have two children, Kristy and Misty. Alfonso is a commercial fisherman and a member of the St. Bernard Coastal Advisory Board and the Knights of Columbus. He was interviewed by Stephanie Scull-DeArmey for the University of Southern Mississippi Center for Oral History and Cultural Heritage on April 24, 2012. Alfonso currently resides in Louisiana and has been a commercial fisherman for a significant period.